History

PCOS seems to have dated back to the 1700’s , however, formal diagnosis criteria was not presented until the 1990’s.

1721

  • An Italian physician and medical scientist named Vallisneri described, “a married, infertile woman with shiny ovaries with a white surface and the size of ovaries as pigeon eggs” (Szydlarska et al., 2017).

1844

  • Bulius and Kretschmar described the presence of nests or clusters in the ovaries, also known as hyperthecosis.

1879

  • Lawson Tait suggested total removal of the ovaries to treat these cysts.

1915

  • Total ovarian resection is criticized, John McGlinn suggests puncturing the cysts on the surface.

1935- Stein and Leventhal

  • Presented a group of seven women with similar characteristics such as hirsutism, menstrual disturbances, and enlarged ovaries with the presence of follicles.
  • Suggested using an ovarian wedge resection for treatment.
  • Method showed to be successful in regulating menstrual cycles.
Irving F. Stein (left), Michael L. Leventhal (right)

1990’s

  • National Institutes of Health (NIH) held PCOS conference to create and propose formal diagnosis criteria.
  • NIH criteria includes: symptoms of excess androgens, rare ovulations, and exclusion of other disorders with similar clinical symptoms.

2003